A cabazitaxel liposome for increased solubility, enhanced antitumor effect and reduced systemic toxicity
نویسندگان
چکیده
منابع مشابه
Enhanced Antitumor Efficacy and Reduced Systemic Toxicity of Sulfatide-Containing Nanoliposomal Doxorubicin in a Xenograft Model of Colorectal Cancer
Sulfatide is a glycosphingolipid known to interact with several extracellular matrix proteins, such as tenascin-C which is overexpressed in many types of cancer including that of the colon. In view of the limited success of chemotherapy in colorectal cancer and high toxicity of doxorubicin (DOX), a sulfatide-containing liposome (SCL) encapsulation approach was taken to overcome these barriers. ...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical Sciences
سال: 2019
ISSN: 1818-0876
DOI: 10.1016/j.ajps.2018.10.004